While Sanger sequencing was highly accurate and less labor-intensive than its predecessors, it still required the use of radioactive reagents and manual sequence recording. In 1986, Leroy Hood’s lab at Caltech replaced the radiolabeled ddNTPs with fluorescently labeled nucleotides, using fluorophores that emitted different colors of light for each base. They were now able to run the products of all four reactions on the same gel and have a computer read the sequence by detecting the color of each fluorescent signal as fragments passed through a laser beam.
�@�{�̑����p�̃����R�����t���A�����Ńt�@�C�����Đ������I�[�g�v���C�@�\��s�[�g�Đ��@�\�A�X���C�h�V���[�@�\�Ȃǂ𗘗p�ł����B
，推荐阅读体育直播获取更多信息
3月1日，美国第五舰队司令部所在的巴林贾法尔海军基地在开战后仅三小时便被多枚导弹和“目击者-136”巡飞弹击中，岸上的仓储区化作一片浓烟。由于深知巴林距伊朗仅两百多公里，面对大量伊朗近程导弹难有侥幸，驻扎港内的数艘美国海军濒海战斗舰和伯克级驱逐舰在几天前就撤离了。
Фото: Majid Asgaripour / WANA / Reuters